<p><strong>About the Role</strong></p> <p>As Director, Pharmacokinetics, you'll shape the scientific and strategic direction of pharmacokinetics, drug metabolism, bioanalysis, and translational PK/PD across our entire portfolio. Working at the intersection of discovery, nonclinical development, clinical development, and regulatory strategy, you'll generate the PK insights that move programs forward — and the decisions that matter most to patients.</p> <p>You'll design pharmacokinetic strategies tailored to each stage of development, lead internal and external activities, and partner closely with cross-functional teams to guide candidate selection, clinical dose planning, and regulatory submissions — turning scientific rigor into real progress for patients.</p> <p><strong>Let’s talk about how you’ll make an impact:</strong></p> <ul> <li>Serve as Tarsus’s expert in pharmacokinetics and DMPK, shaping strategy across every program.</li> <li>Architect and drive PK, DMPK, bioanalytical, and translational PK/PD strategies that carry programs from early discovery all the way through clinical development.</li> <li>Design, lead, and interpret pharmacokinetic, metabolism, disposition, bioanalytical, and PK/PD nonclinical studies.</li> <li>Drive human PK projections, dose and regimen selection, and interpretation of emerging clinical data.</li> <li>Select and lead CROs, laboratories, consultants, and other external partners — assuring study quality, data integrity, and timelines.</li> <li>Review study protocols, reports, and datasets, identify pharmacokinetic and drug-metabolism risks early, and chart the development strategies.</li> <li>Author and review the pharmacokinetics, bioanalytical, and related sections of regulatory documents — including INDs, CTAs, investigator brochures, and briefing documents.</li> <li>Represent Pharmacokinetics on cross-functional project teams and governance forums, translating complex science into clear, actionable recommendations leadership can act on.</li> <li>Oversee the deployment, standardization, and routine execution of Phoenix WinNonlin and related modeling platforms for data analysis.</li> </ul> <p><strong>Driving Innovation, Inside and Out:</strong></p> <ul> <li>Partner with our Innovation Lab and Business Development team to evaluate new assets, surfacing the risks and opportunities that shape what we pursue next.</li> <li>Scout and bring in new methods, AI technologies, and external capabilities that sharpen pharmacokinetic prediction, accelerate development, and improve the quality of every program decision.</li> <li>Cultivate strong scientific relationships, inside Tarsus and out, that push development forward.</li> </ul> <p><strong>Factors for Success:</strong></p> <ul> <li><strong>Decision Making</strong> - Demonstrates strong decision-making by applying structured analysis to complex challenges, balancing competing priorities and long-term impacts while engaging stakeholders and driving solutions aligned with organizational goals.</li> <li><strong>Collaboration and Team Building</strong> - Promotes collaboration by aligning diverse teams around shared goals, fostering healthy debate to advance outcomes, and building strong networks that strengthen organizational effectiveness and cross-team learning.</li> <li><strong>Outcome Driven</strong> - Demonstrates strong outcomes focus by aligning teams around shared priorities, proactively addressing risks and dependencies, and driving cross-functional accountability to sustain progress and deliver results.</li> <li><strong>Empowering Others - </strong>Fosters empowerment by aligning authority with accountability, developing leaders’ decision-making capability, and creating systems that support performance and growth.</li> <li><strong>Emotional Intelligence</strong> - Foster trust and psychological safety, navigating complex interpersonal dynamics with compassion and accountability, and adapting leadership style to support others while maintaining composure under pressure.</li> </ul> <p><strong>Minimum Requirements/Qualifications:</strong></p> <ul> <li>An advanced degree in pharmacokinetics, pharmaceutical sciences, pharmacology, chemistry, biochemistry, biomedical engineering, or a related scientific field and a minimum of 10 years relevant experience; candidates with a bachelor’s or master’s degree and equivalent relevant experience (> 15 yrs) are also encouraged to apply.</li> <li>Substantial industry experience in pharmacokinetics, DMPK, bioanalysis, clinical pharmacology, pharmacometrics, or a related drug-development discipline.</li> <li>A track record of driving impact across drug discovery, nonclinical development, and/or clinical development programs.</li> <li>Deep, broad command of pharmacokinetics, drug metabolism, bioanalysis, and how PK/PD data can sharpen development decisions.</li> <li>Experience working with external research organizations, laboratories, or other development partners.</li> <li>Experience preparing, reviewing, or contributing to scientific and regulatory documentation.</li> <li>A gift for translating complex scientific data into clear, actionable recommendations for cross-functional teams and leaders.</li> <li>Strong written, verbal, organizational, and project-management skills.</li> <li>A collaborative, proactive scientist who thrives in a fast-paced, matrixed environment.</li> <li>An entrepreneurial mindset and an own