Senior Scientist, Analytical Sciences

<div class="content-intro"><h2><span data-contrast="none">About Varda</span></h2> <p>Low Earth orbit is open for business. Varda is accelerating the development of commercial space infrastructure, from in-orbit pharmaceutical processing to reliable and economical reentry capsules. <strong>Varda’s W-Series vehicles are built, designed, and operated by Varda in-house, including the pharmaceutical processing payloads, the capsules, the C-PICA heat shields, and the satellite buses.</strong></p> <p>From life-saving pharmaceuticals to more powerful fiber optics, there is a world of products used on Earth today that can only be manufactured in space. Varda is accelerating innovation in the orbital economy by creating both the products and infrastructure needed so space can directly benefit life on Earth. Our mission is to expand the economic bounds of humankind.  </p> <p>Our team is uniquely suited to accomplishing this goal, with leadership and staff comprised of veterans from SpaceX, Blue Origin, major pharmaceutical companies and Silicon Valley. Varda was founded in January 2021 by Will Bruey and Delian Asparouhov with significant backing from world class investors including Khosla Ventures, Lux Capital, Founders Fund, Caffeinated Capital, General Catalyst, and Also Capital.  </p> <p>Varda is headquartered in El Segundo, California, where we have offices and a production facility where our vehicles, equipment, and materials are built, integrated, and tested. Varda also has offices in Washington, DC and Huntsville, AL. </p> <p>Join Varda, and work to create a bustling in-space ecosystem.</p></div><h2><span data-ccp-props="{"201341983":0,"335559685":0,"335559739":160,"335559740":259}">About this Role</span></h2> <p>Our pharmaceutical R&D team is looking for highly motivated and creative Senior Scientist, Analytical Sciences who will lead efforts in improving therapeutics with microgravity. This is an opportunity in an exciting area of growth for Varda, the role will shape Varda’s product culture and will play a significant role in establishing the low earth orbit economy.</p> <h2>Responsibilities</h2> <ul> <li><span data-contrast="auto">Develop, optimize and validate analytical methods for characterizing biologic and small molecule drug substances and drug products using LC-MS and other biophysical analytical techniques</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Participate in project planning, resource mapping, and timeline scheduling to ensure product development and flight schedules are maintained.</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Carry out hands-on experiments and work with external testing sites to fully characterize drug substances and drug products</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Train junior scientists on techniques and ensure high quality analytical data is produced by Varda</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Collaborate closely with product development, formulation sciences, and broader engineering groups to drive drug development activities </span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Author relevant documents such as methods, protocols, validation reports, and regulatory filings as needed</span><span data-ccp-props="{}"> </span></li> </ul> <h2>Basic Qualifications</h2> <ul> <li><span data-contrast="auto">M.S., or Ph. D. degree in Chemistry, Biochemistry, Chemical Engineering, Materials Science or related fields</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">3+ years of experience with Ph.D., 6+ years of experience with M.S.</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Track record of developing methods for use in regulated filings and workflows</span><span data-ccp-props="{}"> </span></li> </ul> <h2>Preferred Skills and Experience</h2> <ul> <li><span data-contrast="auto">Ph. D in Analytical Chemistry, Pharmaceutical, or Biotechnology degree, with 4+ years of pharmaceutical industry experience developing characterization methods for biologics and small molecule APIs.</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Extensive experience in developing, optimizing, and troubleshooting intact, subunit, and peptide map LC-MS analysis of complex biologics</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Experience with UV, DLS, DSF, NMR, CD, FTIR, Raman, and particle sizing technologies</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Experience with chromatographic and affinity-based methods (HPLC/UPLC, LC-MS/MS, SEC-MALS, GC-MS, CE-SDS, icIEF, SDS-PAGE)</span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Track record of method development as demonstrated by publ