<div class="content-intro"><h2><strong>A Rare Opportunity to Shape the Future of Genomics</strong></h2> <p>Join a team of brilliant, passionate innovators determined to transform healthcare. At BillionToOne, we've built a category-defining, publicly traded company on Nasdaq where transparency fuels trust, collaboration drives breakthroughs, and every contribution moves the needle on our mission to make life-changing diagnostics accessible to all. We don't just aim for incremental improvements; we build products that are 10x better than anything that exists today.</p> <p>Our scientists, engineers, sales executives, and visionaries are united by an unwavering commitment to changing the standard of care in prenatal and cancer diagnostics. This is where cutting-edge science meets human compassion, and every innovation you contribute helps remove the fear of the unknown from some of life's most critical medical moments.</p> <p>If you're driven by purpose, energized by innovation, and ready to help shape the future of precision medicine at scale, this is where you belong.</p></div><p>We are seeking exceptional entrepreneurial builders to join BillionToOne's newly launched <strong>Founder in Residence Program</strong> as a <strong>Director, Office of the CEO</strong>. In this 12 to 18 month program, you will work directly with the CEO and Chief of Staff on the company's highest-priority strategic and operational projects, and graduate into a permanent senior operating role at the Director or Senior Director level.</p> <p>This is one of the highest-leverage roles at BillionToOne. You will be deployed onto a portfolio of high-impact projects each quarter — from new product launches, to commercial strategy, to operational turnarounds, to incubating new business lines and capabilities. Your portfolio of 1-2 projects will be revisited each quarter so you are always working on what matters most to the company.</p> <p>The ideal candidate is a first-principles thinker, a builder, AI-native, and exceptionally sharp. You have founded a company, operated at the most senior level of a top scaleup, or built a track record of high-impact strategic work, and you are looking for your next high-leverage seat — one that gives you scale, mission, and direct CEO exposure without starting from scratch.</p> <p>This role is a hybrid (onsite 3 days/week) position and reports directly to the VP of Business Operations and Chief of Staff, with active co-sponsorship from the CEO.</p> <p><strong>Responsibilities:</strong></p> <ul> <li><strong>Own CEO-Priority Projects:</strong> Lead one or more of BillionToOne's highest-priority strategic and operational initiatives each quarter, sourced directly from the CEO and Office of the CEO. Project types span new product launch support, commercial and go-to-market strategy, business development, operational excellence, competitive response, and the incubation of new business lines.</li> <li><strong>Find Broken Things and Fix Them:</strong> Identify under-performing processes, workflows, or functions. Diagnose root cause, design the fix, and drive execution end-to-end with cross-functional teams.</li> <li><strong>Cross-Functional Leadership:</strong> Lead and influence cross-functional teams across Sales, Product, Lab Operations, Compliance, Reimbursement, Finance, BD, Legal, and HR. Build deep working knowledge of how each function operates through the projects you lead.</li> <li><strong>Operate with AI:</strong> Drive results in ambiguous, fast-moving environments. Use first-principles thinking and AI-native fluency to move faster than the company would otherwise be able to.</li> <li><strong>CEO and Executive Partnership:</strong> Participate in CEO meetings, present to the executive team on an ongoing basis, and serve as a trusted thought partner to the CEO and Chief of Staff on company-shaping decisions.</li> </ul> <p> </p> <p><strong>Qualifications:</strong></p> <ul> <li>6-10+ years of building or operating experience, with a track record of exceptional impact in entrepreneurial or builder-oriented environments</li> <li>One of the following backgrounds: founder of a company that has since been acquired, wound down, or moved on from; senior executive (COO, CPO, VP-level) who joined a top scaleup as one of its first 5 to 10 employees; or top-tier management consultant from MBB or a top boutique firm with healthcare or life sciences exposure, with some operational experience under your belt. </li> <li>First-principles thinker with exceptional analytical horsepower</li> <li>Builder mentality — bias to action, comfort with ambiguity, ability to operate without a playbook</li> <li>AI-native fluency in using AI tools to move faster and amplify individual leverage</li> <li>Strong written and verbal communication, including with executives and the Board</li> <li>Genuine interest in molecular diagnostics and the BillionToOne mission</li> <li>On-site position (relocation to SF Bay Area required)</li> </ul> <p><strong>Nice-To-Haves:</strong></p> <ul> <li>Prior exposure to healthcare, life sciences, molecular diagnostics, or other regulated industries</li> <li>Track record of building 0 to 1 — new products, new functions, new business lines, or new operating mechanisms</li> <li>Existing network in the founder community, YC ecosystem, or top scaleup operating community</li> </ul> <p><strong>Benefits And Perks:</strong></p> <ul> <li>Working