Executive Director, Global Program Leader

<div class="content-intro"><p><span style="font-family: arial, helvetica, sans-serif; font-size: 10pt;">Legend Biotech is a global biotechnology company dedicated to treating and, one day, curing life-threatening diseases. Headquartered in Bridgewater, New Jersey, we are advancing the next generation of cell therapy through a portfolio of innovative technologies, including autologous, allogeneic, and in vivo cell therapy approaches. Our research spans chimeric antigen receptor T-cell (CAR-T), T-cell receptor (TCR-T), natural killer (NK) cell-based therapies, and other emerging platforms designed to transform the treatment of serious diseases. From our global network of research and development sites, we are committed to discovering and developing safe, effective, and cutting-edge therapies for patients worldwide.</span></p> <p><span style="font-family: arial, helvetica, sans-serif; font-size: 10pt;">Legend Biotech entered into a global collaboration agreement with Johnson & Johnson to jointly develop and commercialize CARVYKTI® (ciltacabtagene autoleucel; cilta-cel). Through this strategic partnership, we combine complementary expertise and capabilities to advance innovative immunotherapies for patients living with multiple myeloma.</span></p></div><p><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Legend Biotech is seeking an Executive Director, Global Program Leader as part of the <strong>Research & Development</strong> team based in<strong> Somerset, NJ</strong>.</span></p> <p><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;"><strong>Role Overview</strong></span></p> <p><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">The Executive Director, Global Program Leader (GPL) is a senior strategic leadership role responsible for the overall development, execution, and governance of Legend Biotech's in </span><br><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">vivo CAR-T programs.</span></p> <p><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Reporting directly to the President of R&D, the GPL serves as the single point of accountability for leading cross-functional teams to define and execute integrated global development strategies from IND enabling through clinical proof-of-concept, late-stage </span><br><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">development, registration, and lifecycle management. The GPL ensures alignment of program strategy, timelines, resources, and operational execution across Research, Clinical Development, Regulatory Affairs, Translational Sciences, Technical Development, Manufacturing, Commercial, Business Development, and other key functions.</span></p> <p><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">The successful candidate will combine strong scientific and clinical development expertise with exceptional leadership, strategic thinking, and execution capabilities to advance innovative in vivo CAR-T therapies for patients worldwide.</span></p> <p><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;"><strong>Key Responsibilities</strong></span></p> <ul> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Lead the overall strategy and execution of assigned in vivo CAR-T programs across the development lifecycle.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Develop and maintain integrated global development plans that align scientific, clinical, regulatory, manufacturing, and commercial objectives.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Serve as the primary strategic leader and accountable executive for program success, key deliverables, timelines, budgets, and milestones.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Drive portfolio decision-making by evaluating benefit-risk profiles, competitive landscapes, development options, and investment priorities.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Ensure alignment of program strategies with corporate objectives and portfolio priorities.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Lead the formulation and execution of global clinical development and registration strategies for in vivo CAR-T assets.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Partner closely with Clinical Development and Regulatory Affairs to design efficient development pathways that maximize speed to proof-of-concept, pivotal development, and global approvals.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Guide critical regulatory interactions and major health authority milestones.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Ensure readiness and alignment for INDs, CTAs, BLA/MAA submissions, and lifecycle management activities.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-size: 12pt;">Chair Global Program Teams and provide leadership across all functional areas involved in program execution.</span></li> <li><span style="font-family: arial, helvetica, sans-serif; font-si