<div class="content-intro"><p><strong>About Us</strong><strong>…</strong></p> <p>Obsidian Therapeutics is pioneering engineered cell and gene therapies to deliver transformative outcomes for patients. Obsidian’s programs apply our <span data-olk-copy-source="MessageBody">cytoDRiVE®</span> technology in Cell and Gene therapy products to control expression of proteins for enhanced therapeutic efficacy and safety. Obsidian’s lead program is currently in clinical development for the treatment of patients with metastatic melanoma and <span data-olk-copy-source="MessageBody">non-small cell lung cancer.</span></p> <p>We’re proud of our diverse talented team and committed to cultivating an environment of inclusion where each person feels a strong sense of belonging and is supported to continuously learn and contribute their best work. Our Research team is based in the heart of Cambridge, MA, and Technical Operations team is based in our purpose built facility in Bedford, MA. Obsidianites enjoy a highly collaborative culture, competitive salary and benefits, and potential for ownership through stock options.</p></div><p><strong>Our Opportunity...</strong></p> <p><span data-contrast="none">We are looking for a highly motivated, collaborative, sophisticated data scientist for our Associate Director of Process Data Analytics role, with strong CMC domain expertise and advanced statistical modeling experience. As a key contributor within our Process Development and MSAT team, this hands-on and strategic leader will define and deliver advanced analytics, statistical modeling, and fit for purpose data infrastructure for real time monitoring of cell and gene therapy manufacturing processes,</span> <span data-contrast="none">helping to drive the late-stage development of our first clinical stage autologous cell therapy program targeting solid tumors.</span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="none">You’ll </span><span data-contrast="none">translate multi-dimensional process and product datasets into actionable insights that deepen understanding, inform CMC decision making, support regulatory submissions, and strengthen data driven execution. Partnering cross-functionally and with external partners, you’ll ensure data integrity and drive the compliant integration of AI/ML tools to accelerate manufacturing intelligence</span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="none">As a member of our Process Development and </span><span data-contrast="auto">MSAT team, yo</span><span data-contrast="none">u will be a vital part of a highly collaborative group working to unlock the promise of precision cell therapy for patients, starting with our lead program amsoki-cel (OBX-115), a novel engineered tumor-infiltrating lymphocyte (TIL) cell therapy that uses our proprietary cytoDRiVE® platform. This is a unique opportunity to be a valuable contributor in a well-funded clinical company with field-leading advisors, best-in-class partners, and an experienced team. </span><span data-contrast="auto"> </span><span data-ccp-props="{}"> </span></p> <p><strong>You Will...</strong></p> <p><em>Core responsibilities</em></p> <ul> <li><span data-contrast="none">Deliver sophisticated statistical modeling, process monitoring, and visualization of datasets across manufacturing lines. </span><span data-ccp-props="{"335557856":16777215}"> </span></li> <li><span data-contrast="auto">Synthesize complex technical data for cross-functional governance and leadership forums, and partner with Process Development, Analytical Development, Quality Control, Quality Assurance, CMOs, CMC teams, executive leadership, to translate into operational and regulatory insights. </span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Establish data infrastructure to seamlessly collect, clean, store, and analyze manufacturing and quality data across both paper and electronic sources including Electronic Batch Records (EBR), Manufacturing Execution Systems (MES), Laboratory Information Management Systems (LIMS), and Supervisory Control and Data Acquisition(SCADA), and related systems. </span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Act as the primary business owner for technical databases, ensuring cross-functional alignment between Process Development, Quality Assurance, and Contract Manufacturing Organizations (CMOs). </span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Build and manage interactive dashboards using platforms like Tableau, Power BI, or Spotfire to deliver real-time process monitoring to executive leadership and CMC team. </span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Author and review CMC technical documentation, data trending summaries, process validation protocols, and other input to CMC regulatory sections for BLA/MAA submissions. </span><span data-ccp-props="{}"> </span></li> <li><span data-contrast="auto">Lead the establishment of the process monitoring program by applying statistical process control methodologies (SPC). Provide insights for establishment of in-process control ranges, and statistical justification for release attributes. </span><span data-ccp-props="{}"> </span></