<div class="content-intro"><p><strong>About Us</strong><strong>…</strong></p> <p>Obsidian Therapeutics is pioneering engineered cell and gene therapies to deliver transformative outcomes for patients. Obsidian’s programs apply our <span data-olk-copy-source="MessageBody">cytoDRiVE®</span> technology in Cell and Gene therapy products to control expression of proteins for enhanced therapeutic efficacy and safety. Obsidian’s lead program is currently in clinical development for the treatment of patients with metastatic melanoma and <span data-olk-copy-source="MessageBody">non-small cell lung cancer.</span></p> <p>We’re proud of our diverse talented team and committed to cultivating an environment of inclusion where each person feels a strong sense of belonging and is supported to continuously learn and contribute their best work. Our Research team is based in the heart of Cambridge, MA, and Technical Operations team is based in our purpose built facility in Bedford, MA. Obsidianites enjoy a highly collaborative culture, competitive salary and benefits, and potential for ownership through stock options.</p></div><p><strong>Our Opportunity...</strong></p> <p><span data-contrast="auto">We’re seeking an<strong> Associate Director/Director, CMC Digital Business Partner</strong>, to work closely with Technical Operations leadership to define, deliver, and maintain the digital systems needed to support and enable Obsidian’s GMP operations strategy. In this role, you will partner with the Tech Ops/CMC business systems owners to translate business needs into inspection-ready digital capabilities aligned to the business’ priorities and milestones (including BLA readiness and commercial launch) and approved budget. Near term priorities include cell orchestration (chain of identity and custody), process data history and analytics, eQMS/document control, and ERP integration. </span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">In partnership with business system owners, you will select, implement, validate, integrate, support, and continuously improve key CMC digital platforms across internal and external operations through direct execution and engagement and oversight of consultants, systems integrators, and managed-service partners where warranted. The successful candidate will be highly collaborative and committed to understanding how the business runs in the internal processing suites, analytical labs, and partner interfaces. </span><span data-ccp-props="{}"> </span></p> <p><span data-contrast="auto">As a member of our Digital Solutions & Technology team, you will be a vital part of a highly collaborative group working to unlock the promise of precision cell therapy for patients, starting with our lead program amsoki-cel (OBX-115), a novel engineered tumor-infiltrating lymphocyte (TIL) cell therapy that uses our proprietary cytoDRiVE® platform. This is a unique opportunity to be a valuable contributor in a well-funded clinical company with field-leading advisors, best-in-class partners, and an experienced team. </span><span data-ccp-props="{}"> </span></p> <p><strong><span data-contrast="auto">This is a hybrid role based in Bedford, MA, with periodic travel to CDMO and/or partner sites as needed.</span><span data-ccp-props="{}"> </span></strong></p> <p><strong>You Will...</strong></p> <p><em>Core responsibilities</em></p> <ul> <li><span data-contrast="auto"><span data-ccp-charstyle="normaltextrun" data-ccp-charstyle-defn="{"ObjectId":"ac0262f4-8a9e-5820-b908-2d943c5f7113|1","ClassId":1073872969,"Properties":[201342446,"1",201342447,"5",201342448,"1",201342449,"1",469777841,"Calibri",469777842,"Arial",469777843,"Calibri",469777844,"Calibri",201341986,"1",469769226,"Calibri,Arial",268442635,"22",469775450,"normaltextrun",201340122,"1",134233614,"true",469778129,"normaltextrun",335572020,"1",469778324,"Default Paragraph Font"]}">Serve as the embedded digital business partner for </span><span data-ccp-charstyle="normaltextrun">Tech Ops</span><span data-ccp-charstyle="normaltextrun">/CMC, building trusted relationships with Manufacturing, MSAT/Process Development, Analytical Development, Quality, Supply Chain, </span><span data-ccp-charstyle="normaltextrun">CMC </span><span data-ccp-charstyle="normaltextrun">Regulatory, Facilities, </span><span data-ccp-charstyle="normaltextrun">CMC Program Management </span><span data-ccp-charstyle="normaltextrun">and external partners</span><span data-ccp-charstyle="normaltextrun"> as needed</span><span data-ccp-charstyle="normaltextrun">. </span></span><span data-ccp-props="{"201341983":0,"335559739":160,"335559740":259}"> </span></li> <li><span data-contrast="auto">Partner with Tech Ops/CMC leadership to develop and deliver the CMC digital strategy, roadmap, and systems portfolio, serving as T</span><span data-contrast="auto">echnical </span><span data-contrast="auto">System Owner for platforms supporting manufacturing execution, cell orchestration/COI-COC, laboratory informatics, logistics/ distribution, quality </span><span data-contrast="auto"><span data-ccp-charstyle="normaltextrun">operations, and ERP integration; aligned with BLA and commercial launch</span> </span><span data-contrast="auto"><span data-ccp-charstyle="normaltextrun">readiness</span></span><span data-contrast="auto"><